<div id="cookie_notice" class="sw-row sw--padding-2 sw--padding-bottom-1-force sw--text-center sw--bg-grey" > <div class="col-1-2 col-1-1--tab col--no-padding sw--display-inline-block sw--float-none sw--text-left sw--vertical-align__middle"> <p class="col-1-2 col--no-padding small">We use cookies to offer you a better browsing experience. By continuing to use the site you agree to their use. You can find out more about our cookies and read our privacy policy <a href="/legal/privacy-statement" target="_blank">here.</a></p> <div class="col-1-2 col--no-padding sw--text-center"> <div class="col-1-2 col--no-padding sw--display-inline-block sw--float-none"> <a class="sw-dms-button noty_close col-1-1 col--no-padding" data-sw-set-cookie="euCookie">OK</a> </div> </div> </div> </div>

<div class="sw--display-block sw--text-white" style="background-color: #1e2740"> <div id="emailModalContentContainer"> <span class="noty_close sw--position-absolute sw--position-right sw--padding-top-3 sw--padding-right-3 icon-cancel sw--opacity-8 sw--z-index-10"></span> <div class="sw-row"> <div class="sw--position-relative sw--display-block sw--padding-3" style="min-width: 380px"> <p class="sw--font-size-16 sw--margin-bottom-2 sw--margin-right-6">Sign up to hear about special promotions</p> <form action="/register/email-signup" class="sw--position-relative" data-confirmation="emailConfirmationModal" data-sw-email-modal-form> <input type="text" class="sw--input-height__medium" style="width:60%;" placeholder="Email address" name="email" /> <input type="hidden" class="" name="location" value="/product/YJ3JWGGA8/monoclonal-igg4-antibody-bound-to-pd-1-5dk3-5ggr" /> <input type="hidden" class="" name="confirmation" value="emailConfirmationModal" /> <input type="submit" class="btn-primary sw--margin-left-1" value="Subscribe" /> <div id="emailModalFormError" class="text-error" style="display:none"></div> </form> </div> </div> </div>

Click and drag to rotate
Monoclonal IgG4 Antibody bound to PD-1 5dk3 5ggr 3d printed

Not a Photo

Glossy Full Color Sandstone
Monoclonal IgG4 Antibody bound to PD-1 5dk3 5ggr 3d printed
Monoclonal IgG4 Antibody bound to PD-1 5dk3 5ggr 3d printed

Not a Photo

Monoclonal IgG4 Antibody bound to PD-1 5dk3 5ggr

Made by
3D printed in fully colored material with a glossy and smooth finish.
All orders are backed by our
All orders are backed by our
Money Back Guarantee.
Product Description
Model Description
This is a 3D print of a humanized monoclonal IgG4 antibody used in multiple types of cancer treatments. Protein is visualized to distinguish each chain of the antibody in different shades of green and PD-1 red. This model was created from PDB IDs: 5dk3 and 5ggr. 
Protein Description
This is a 3D print of a humanized antibody used in cancer immunotherapy. This type of antibody is known as "IgG4," and works on the surface of white blood cells to block a protective mechanism of cancer. Without this protective mechanism, the antibody allows the immune system to destroy those cancer cells. Specifically, this IgG4 antibody targets the programmed cell death 1(PD-1) receptor.

The PD-1 receptor usually stops the immune system from attacking its own tissue. Cancer cells produce a compound that stimulates the white blood cell's PD-1 receptor, stopping the white blood cell from killing the cancer cells. Blocking this receptor with antibodies allows the immune system to re-engage with diseased tissue and kill undesirable cells. Because of this type of mechanistic intervention, adverse effects are possible like inflammation and even type 1 diabetes.  

Despite the adverse risks, antibodies like this are at the forefront of medicine, providing people with untreatable types of cancers with a new approach to improving patient outcomes. 
What's in the box:
Sml: Pembrolizumab PD1
6.73 x 7.64 x 3.78 cm
Switch to inches
2.65 x 3.01 x 1.49 inches
Switch to cm
Success Rate:
First To try.
What's this?
Mature audiences only.
Sign In or Join to comment.


We're sorry to inform you that we no longer support this browser and can't confirm that everything will work as expected. For the best Shapeways experience, please use one of the following browsers:

Click anywhere outside this window to continue.