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Monoclonal IgG4 Antibody bound to PD-1 5dk3 5ggr 3d printed

DIGITAL PREVIEW
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Glossy Full Color Sandstone
Monoclonal IgG4 Antibody bound to PD-1 5dk3 5ggr 3d printed
Monoclonal IgG4 Antibody bound to PD-1 5dk3 5ggr 3d printed

DIGITAL PREVIEW
Not a Photo

Monoclonal IgG4 Antibody bound to PD-1 5dk3 5ggr

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$77.64
3D printed in fully colored material with a glossy and smooth finish.
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Product Description
Model Description
This is a 3D print of a humanized monoclonal IgG4 antibody used in multiple types of cancer treatments. Protein is visualized to distinguish each chain of the antibody in different shades of green and PD-1 red. This model was created from PDB IDs: 5dk3 and 5ggr. 
Protein Description
This is a 3D print of a humanized antibody used in cancer immunotherapy. This type of antibody is known as "IgG4," and works on the surface of white blood cells to block a protective mechanism of cancer. Without this protective mechanism, the antibody allows the immune system to destroy those cancer cells. Specifically, this IgG4 antibody targets the programmed cell death 1(PD-1) receptor.

The PD-1 receptor usually stops the immune system from attacking its own tissue. Cancer cells produce a compound that stimulates the white blood cell's PD-1 receptor, stopping the white blood cell from killing the cancer cells. Blocking this receptor with antibodies allows the immune system to re-engage with diseased tissue and kill undesirable cells. Because of this type of mechanistic intervention, adverse effects are possible like inflammation and even type 1 diabetes.  

Despite the adverse risks, antibodies like this are at the forefront of medicine, providing people with untreatable types of cancers with a new approach to improving patient outcomes. 
Details
What's in the box:
Sml: Pembrolizumab PD1
Dimensions:
6.73 x 7.64 x 3.78 cm
Switch to inches
2.65 x 3.01 x 1.49 inches
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Success Rate:
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Rating:
Mature audiences only.
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