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THC Cannabinoid Receptor Complex 5tgz 3d printed

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Not a Photo

Glossy Full Color Sandstone
THC Cannabinoid Receptor Complex 5tgz 3d printed
THC Cannabinoid Receptor Complex 5tgz 3d printed

DIGITAL PREVIEW
Not a Photo

THC Cannabinoid Receptor Complex 5tgz

Made by
$80.11
3D printed in fully colored material with a glossy and smooth finish.
QTY
Product Description
3D print of a THC Cannabinoid Receptor Complex. Model created from PDB ID: 5tgz.
Model Description
This 3D printed protein model of a THC (red) Cannabinoid Receptor (blue-green) Complex is visualized as a volumetric surface and colored by the protein's bFactor. 
Protein Description
Cannabinoid receptor 1 (CB1) is the principal target of ?(9)-tetrahydrocannabinol (THC), a psychoactive chemical from Cannabis sativa with a wide range of therapeutic applications and a long history of recreational use. CB1 is activated by endocannabinoids and is a promising therapeutic target for pain management, inflammation, obesity, and substance abuse disorders. Here, we present the 2.8 Å crystal structure of human CB1 in complex with AM6538, a stabilizing antagonist, synthesized and characterized for this structural study. The structure of the CB1-AM6538 complex reveals key features of the receptor and critical interactions for antagonist binding. In combination with functional studies and molecular modeling, the structure provides insight into the binding mode of naturally occurring CB1 ligands, such as THC, and synthetic cannabinoids. This enhances our understanding of the molecular basis for the physiological functions of CB1 and provides new opportunities for the design of next-generation CB1-targeting pharmaceuticals. "
http://www.rcsb.org/pdb/explore/explore.do?structureId=5tgz
Details
What's in the box:
Mdm: THC Cannabanoid Receptor Complex
Dimensions:
6.26 x 9.02 x 6.2 cm
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2.47 x 3.55 x 2.44 inches
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Success Rate:
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Rating:
Mature audiences only.
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