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Phage T4 Helicase bound to Single Stranded DNA 3d printed

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Glossy Full Color Sandstone
Phage T4 Helicase bound to Single Stranded DNA 3d printed
Phage T4 Helicase bound to Single Stranded DNA 3d printed

DIGITAL PREVIEW
Not a Photo

Phage T4 Helicase bound to Single Stranded DNA

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$62.21
3D printed in fully colored material with a glossy and smooth finish.
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Product Description
Protein Description
Helicases move on DNA via an ATP binding and hydrolysis mechanism coordinated by well-characterized helicase motifs. However, the translocation along single-stranded DNA (ssDNA) and the strand separation of double-stranded (dsDNA) may be loosely or tightly coupled. Dda is a phage T4 SF1B helicase with sequence homology to the Pif1 family of helicases that tightly couples translocation to strand separation. The crystal structure of the Dda-ssDNA binary complex reveals a domain referred to as the "pin" that was previously thought to remain static during strand separation. The pin contains a conserved phenylalanine that mediates a transient base-stacking interaction that is absolutely required for separation of dsDNA. The pin is secured at its tip by protein-protein interactions through an extended SH3 domain thereby creating a rigid strut. The conserved interface between the pin and the SH3 domain provides the mechanism for tight coupling of translocation to strand separation. 

http://www.rcsb.org/pdb/explore.do?structureId=3upu
 
Details
What's in the box:
Mdm: T4 Phage Ribbon
Dimensions:
5.67 x 7.1 x 5.83 cm
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2.23 x 2.79 x 2.3 inches
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Success Rate:
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Rating:
Mature audiences only.
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