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Deoxyhypusine Hydroxylase 3d printed

Not a Photo

Coated Full Color Sandstone
Deoxyhypusine Hydroxylase 3d printed
Deoxyhypusine Hydroxylase 3d printed

Not a Photo

Deoxyhypusine Hydroxylase

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3D printed in fully colored material with a glossy and smooth finish.
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Product Description
Deoxyhypusine hydroxylase (DOHH) is a non-heme diiron enzyme involved in the posttranslational modification of a critical lysine residue of eukaryotic translation initiation factor 5A (eIF-5A) to yield the unusual amino acid residue hypusine. This modification is essential for the role of eIF-5A in translation and in nuclear export of a group of specific mRNAs. The diiron center of human DOHH (hDOHH) forms a peroxo-diiron(III) intermediate (hDOHHperoxo) when its reduced form reacts with O2. hDOHHperoxo has a lifetime exceeding that of the peroxo intermediates of other diiron enzymes by several orders of magnitude. Here we report the 1.7-Å crystal structures of hDOHHperoxo and a complex with glycerol.
What's in the box:
Deoxyhypusine Hydroxylase
7.64 x 7.52 x 5.99 cm
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3.01 x 2.96 x 2.36 inches
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