Natural Full Color Sandstone
Ankyrin Adaptor Protein
Made by
Print With Shapeways
Choose Your Material
Choose your color and finish
Choose Your Material
$47.00
Choose your color and finish
Have a question about this product?
contact the designerYou must be logged in and verified to contact the designer.
Product Description
Full-consensus designed ankyrin repeat proteins (DARPins), in which randomized positions of the previously described DARPin library have been fixed, are characterized. They show exceptionally high thermodynamic stabilities, even when compared to members of consensus DARPin libraries and even more so when compared to naturally occurring ankyrin repeat proteins. We determined the crystal structure of a full-consensus DARPin, containing an N-capping repeat, three identical internal repeats and a C-capping repeat at 2.05 A resolution, and compared its structure with that of the related DARPin library members E3_5 and E3_19. This structural comparison suggests that primarily salt bridges on the surface, which arrange in a network with almost crystal-like regularity, increase thermostability in the full-consensus NI(3)C DARPin to make it resistant to boiling. In the crystal structure, three sulfate ions complement this network.
Request a custom order
and get this product personalized just for you
Details
What's in the box:
Ankyrin Adaptor Protein
Dimensions:
Success Rate:
First To try.
What's this?
Rating:
Mature audiences only.
