Click and drag to rotate
Proteasome 1Q5R 3d printed

DIGITAL PREVIEW
Not a Photo

Glossy Full Color Sandstone
Proteasome 1Q5R 3d printed
Proteasome 1Q5R 3d printed

DIGITAL PREVIEW
Not a Photo

Proteasome 1Q5R

Made by
$46.02
3D printed in fully colored material with a glossy and smooth finish.
QTY

Have a question about this product?

contact the designer
You must be logged in and verified to contact the designer.
Product Description
To understand the role of the pro-peptide in proteasome assembly, we have determined structures of the Rhodococcus proteasome and a mutant form that prevents the autocatalytic removal of its pro-peptides. The structures reveal that the pro-peptide acts as an assembly-promoting factor by linking its own beta-subunit to two adjacent alpha-subunits, thereby providing a molecular explanation for the observed kinetics of proteasome assembly. The Rhodococcus proteasome has been found to have a substantially smaller contact region between alpha-subunits compared to those regions in the proteasomes of Thermoplasma, yeast, and mammalian cells, suggesting that a smaller contact area between alpha-subunits is likely the structural basis for the Rhodococcus alpha-subunits not assembling into alpha-rings when expressed alone. Analysis of all available beta-subunit structures shows that the contact area between beta-subunits within a beta-ring is not sufficient for beta-ring self-assembly without the additional contact provided by the alpha-ring. This appears to be a fail-safe mechanism ensuring that the active sites on the beta-subunits are activated only after proteasome assembly is complete.
Details
What's in the box:
exsm_Proteasome_1Q5R_ml_x50-50_4cm_vA2
Dimensions:
3.15 x 3.15 x 3.97 cm
Switch to inches
1.24 x 1.24 x 1.57 inches
Switch to cm
Success Rate:
First To try.
What's this?
Rating:
Mature audiences only.
Logo

Hello.

We're sorry to inform you that we no longer support this browser and can't confirm that everything will work as expected. For the best Shapeways experience, please use one of the following browsers:

Click anywhere outside this window to continue.