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Seneca Valley virus (SVV) is a small, non-enveloped picornavirus, unknown until 2002 when it was discovered incidentally as a cell culture contaminant. Only a single species is classified in the genus Senecavirus. The family Picornaviridae also contains foot-and-mouth disease virus (FMDV) and swine vesicular disease virus (SVDV). The survival of SVV in the environment has not been reported. Most cases of idiopathic vesicular disease, which is associated with SVV, seem to occur between spring and fall.