You must be logged in and verified to contact the designer.
Say hello to biggest little thing in biotechnology!
This is a model of a guide RNA from the CRISPR/Cas system bound to its target DNA. For a summary of CRISPR/Cas9, see the protein's page. The model is adapted from the crystal structure of a Cas9 protein from the bacterium Staphylococcus aureus. If you are interested in the entire protein/RNA/DNA complex, check out either the mini or mega models. Notice the 180-degree twist of the DNA strand where it is pried apart by protein's Phosphate Lock Loop. This model is also available in either mini and mega.
 Hiroshi Nishimasu et al., "Crystal structure of Staphylococus aureus Cas9." Cell (2015)