Cas13-crRNA Binary Complex

CRISPR-Cas13 also known as CRISPR-Cas Type VI , CRISPR-Cas13a target RNA and previously known as C2c2 is a nucleic acid editing technology, particularly at the RNA level, analogous to the CRISPR / Cas9 system. The CRISPR-Cas Type VI system contains the programmable single-effector RNA-guided RNases with Cas13 and can be manipulated to knockdown and bind (RNA) mammalian cell RNA. CRISPR-Cas13 can be used as a flexible platform to study RNA in mammalian cells and for therapeutic development.