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Human Apoptosome 3d printed

DIGITAL PREVIEW
Not a Photo

Natural Full Color Sandstone
 Human Apoptosome 3d printed
 Human Apoptosome 3d printed

DIGITAL PREVIEW
Not a Photo

Human Apoptosome

Made by
$30.00
3D printed in fully colored material with a coarse finish and a delicate feel.
QTY
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Product Description
Apoptosome assembly is highly regulated in the intrinsic cell death pathway. To better understand this step, we created an improved model of the human apoptosome using a crystal structure of full length Apaf-1 and a single particle, electron density map at ~9.5 Å resolution. The apoptosome model includes N-terminal domains of Apaf-1, cognate propellers, and cytochrome c. A direct comparison of Apaf-1 in the apoptosome and as a monomer reveals conformational changes that occur during the first two steps of assembly. This includes an induced-fit mechanism for cytochrome c binding to regulatory propellers, which is dependent on shape and charge complementarity, and a large rotation of the nucleotide binding module during nucleotide exchange.
Details
What's in the box:
Human Apoptosome
Dimensions:
7.01 x 7.16 x 1.96 cm
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2.76 x 2.82 x 0.77 inches
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Success Rate:
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Rating:
Mature audiences only.
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