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Computationally Designed Top7 Protein 3d printed

Not a Photo

Glossy Full Color Sandstone
Computationally Designed Top7 Protein 3d printed
Computationally Designed Top7 Protein 3d printed

Not a Photo

Computationally Designed Top7 Protein

Made by
Ships as soon as 18 days
3D printed in fully colored material with a glossy and smooth finish.
Product Description
Top7 is an artificial 93-residue protein, classified as a de novo protein since it was designed by Brian Kuhlman and Gautam Dantas in David Baker's laboratory at the University of Washington to have a unique fold not found in nature. The protein was designed ab initio on a computer with the help of protein structure prediction algorithms. Determination of the high-resolution X-ray structure of the experimentally expressed and purified protein revealed that the structure was indeed very similar (1.2 Å RMSD) to the computer-designed model. The structure consists of two alpha helices packed on a five-stranded anti-parallel beta sheet. Top7 was featured as the RCSB Protein Data Bank's 'Molecule of the Month' in October 2005, and a superposition of the respective cores (residues 60-79) of its predicted and X-ray crystal structures are featured in the Rosetta@home logo.

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7.15 x 8.73 x 6.11 cm
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2.81 x 3.44 x 2.41 inches
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