INTRODUCING OUR  HOLIDAY BUSINESS BUNDLE
LEARN MORE

<div id="cookie_notice" class="sw-cookie-notice sw--padding-vert-4 sw--padding-hor-1 sw-dms--box-shadow--big"> <div class="sw-dms--color-white sw-grid-flex sw-grid-flex--wrap-mob sw-grid-flex--wrap--tab"> <div class="sw-cookie-notice__text--mob sw--padding-left-8 sw--font-size-14 sw-grid-flex__cell-5-7 sw-grid-flex__cell-1-1--mob sw-grid-flex__cell-1-1--tab"> We use cookies to offer you a better browsing experience, including personalized advertising. By continuing to use the site you agree to their use. <a href="/legal/privacy-statement" target="_blank">Learn more</a> </div> <div class="sw-grid-flex__cell-2-7 sw-grid-flex__cell-1-1--mob sw-grid-flex__cell-1-1--tab"> <a class="sw-dms-button noty_close sw--padding-hor-7 sw--position-absolute sw--position-right sw--margin-right-13 sw--hide-mobile sw--hide-tablet" data-sw-set-cookie="euCookie">OK</a> <a class="sw-cookie-notice__btn--mob sw-cookie-notice__btn--tab sw-dms-button noty_close sw--padding-hor-7 sw--margin-vert-3 sw--hide-desktop" data-sw-set-cookie="euCookie">OK</a> </div> </div> </div>

<div class="sw--display-block sw-dms--color-white" style="background-color: #1e2740"> <div id="emailModalContentContainer"> <span class="noty_close sw--position-absolute sw--position-right sw--padding-top-3 sw--padding-right-3 icon-cancel sw--opacity-8 sw--z-index-10"></span> <div class="sw-row"> <div class="sw--position-relative sw--display-block sw--padding-3" style="min-width: 380px"> <p class="sw--font-size-16 sw--margin-bottom-2 sw--margin-right-6">Sign up to hear about special promotions</p> <form action="/register/email-signup" class="sw--position-relative" data-confirmation="emailConfirmationModal" data-sw-email-modal-form> <input type="text" class="sw--input-height__medium" style="width:60%;" placeholder="Email address" name="email" /> <input type="hidden" class="" name="location" value="/product/QHATJSAEK/lrg-tetranucelosome-1zbb" /> <input type="hidden" class="" name="confirmation" value="emailConfirmationModal" /> <input type="submit" class="btn-primary sw--margin-left-1" value="Subscribe" /> <div id="emailModalFormError" class="text-error" style="display:none"></div> </form> </div> </div> </div>

Lrg: Tetranucelosome 1zbb 3d printed Picture still generating

DIGITAL PREVIEW
Not a Photo

Picture still generating
Lrg: Tetranucelosome 1zbb 3d printed Picture still generating
Lrg: Tetranucelosome 1zbb 3d printed Picture still generating

DIGITAL PREVIEW
Not a Photo

Lrg: Tetranucelosome 1zbb

Made by
Not For Sale
Product Description

DNA in eukaryotic chromosomes is organized in arrays of nucleosomes compacted into chromatin fibres. This higher-order structure of nucleosomes is the substrate for DNA replication, recombination, transcription and repair. Although the structure of the nucleosome core is known at near-atomic resolution, even the most fundamental information about the organization of nucleosomes in the fibre is controversial. Here we report the crystal structure of an oligonucleosome (a compact tetranucleosome) at 9 A resolution, solved by molecular replacement using the nucleosome core structure. The structure shows that linker DNA zigzags back and forth between two stacks of nucleosome cores, which form a truncated two-start helix, and does not follow a path compatible with a one-start solenoidal helix. The length of linker DNA is most probably buffered by stretching of the DNA contained in the nucleosome cores. We have built continuous fibre models by successively stacking tetranucleosomes one on another. The resulting models are nearly fully compacted and most closely resemble the previously described crossed-linker model. They suggest that the interfaces between nucleosomes along a single helix start are polymorphic. 

Details
Sign In or Join to comment.
 
 
Logo

Hello.

We're sorry to inform you that we no longer support this browser and can't confirm that everything will work as expected. For the best Shapeways experience, please use one of the following browsers:

Click anywhere outside this window to continue.