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4'-Phosphopantetheinyl transferases (PPTase) 3d printed

DIGITAL PREVIEW
Not a Photo

Full Color Sandstone
4'-Phosphopantetheinyl transferases (PPTase) 3d printed
4'-Phosphopantetheinyl transferases (PPTase) 3d printed

DIGITAL PREVIEW
Not a Photo

4'-Phosphopantetheinyl transferases (PPTase)

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OVERVIEW
  • 3D printed in Full Color Sandstone: Fully colored material with a coarse finish and a delicate feel.
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  • This product is intended for mature audiences.
$42.81
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Product Description

3D print of 4'-Phosphopantetheinyl transferases (PPTase), colored by surface bFactor and created from PDB ID: 4QJK.

 

"4'-Phosphopantetheinyl transferases (PPTase) post-translationally modify carrier proteins with a phosphopantetheine moiety, an essential reaction in all three domains of life. In the bacterial genus Mycobacteria, the Sfp-type PPTase activates pathways necessary for the biosynthesis of cell wall components and small molecule virulence factors. We solved the X-ray crystal structures and biochemically characterized the Sfp-type PPTases from two of the most prevalent Mycobacterial pathogens, PptT of M. tuberculosis and MuPPT of M. ulcerans. Structural analyses reveal significant differences in cofactor binding and active site composition when compared to previously characterized Sfp-type PPTases. Functional analyses including the efficacy of Sfp-type PPTase-specific inhibitors also suggest that the Mycobacterial Sfp-type PPTases can serve as therapeutic targets against Mycobacterial infections. " --PDB Citation
 

What's in the Box
INCM
4'-Phosphopantetheinyl transferases (PPTase)
Full Color Sandstone
Width
5.7 cm
Height
4.4 cm
Depth
4.6 cm

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