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Cascade Complex

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Product Description
[color=#5a5a5a]This is a Cascade complex structure based on PDB ID 4QYZ. The structure shows Cascade [/color](CRISPR-associated complex for antiviral defense) in[color=#5a5a5a] action. The structure includes the strand of CRISPR RNA (red) and a short piece of the viral DNA (blue) after it has been unwound and recognized. The structure revealed a surprising but very logical structure for the RNA and DNA. The RNA is stretched open in a long spiral groove in Cascade, and the DNA binds side-by-side, instead of in the classical double helix[/color]
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