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DPP4-Sitagliptin Complex 2P8S 3d printed

Not a Photo

Glossy Full Color Sandstone
DPP4-Sitagliptin Complex 2P8S 3d printed
DPP4-Sitagliptin Complex 2P8S 3d printed

Not a Photo

DPP4-Sitagliptin Complex 2P8S

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Ships as soon as 15 days
3D printed in fully colored material with a glossy and smooth finish.

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Product Description
Molecular modeling was used to design a rigid analog of sitagliptin 1. The X-ray crystal structure of sitagliptin bound to DPP-4 suggested that the central beta-amino butyl amide moiety could be replaced with a cyclohexylamine group. This was confirmed by structural analysis and the resulting analog 2a was synthesized and found to be a potent DPP-4 inhibitor (IC(50)=21 nM) with excellent in vivo activity and pharmacokinetic profile. 
What's in the box:
6.7 x 7.96 x 7 cm
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2.64 x 3.13 x 2.76 inches
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Success Rate:
First To try.
What's this?
Mature audiences only.


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