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Allergen Profilin 3d printed

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Allergen Profilin 3d printed
Allergen Profilin 3d printed

DIGITAL PREVIEW
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Allergen Profilin

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Product Description
Oligomerization of allergens plays an important role in IgE-mediated reactions, as effective crosslinking of IgE- FcRI complexes on the cell membrane is dependent on the number of exposed B-cell epitopes in a single allergen molecule or on the occurrence of identical epitopes in a symmetrical arrangement. Few studies have attempted to experimentally demonstrate the connection between allergen dimerization and the ability to trigger allergic reactions. Here we studied plant allergenic profilins rHev b 8 (rubber tree) and rZea m 12 (maize) because they represent an important example of cross-reactivity in the latex-pollen-food syndrome. Both allergens in their monomeric and dimeric states were isolated and characterized by exclusion chromatography and mass spectrometry and were used in immunological in vitro experiments.
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Allergen Profilin
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