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The P53 gene is important in protecting against DNA damage and the rise of cancers.
Original Source data:
High-resolution structure of the oligomerization domain of p53 by multidimensional NMR.
Clore, G.M., Omichinski, J.G., Sakaguchi, K., Zambrano, N., Sakamoto, H., Appella, E., Gronenborn, A.M.
Journal: (1994) Science 265: 386-391
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The three-dimensional structure of the oligomerization domain (residues 319 to 360) of the tumor suppressor p53 has been solved by multidimensional heteronuclear magnetic resonance (NMR) spectroscopy. The domain forms a 20-kilodalton symmetric tetramer with a topology made up from a... [ Read More & Search PubMed Abstracts ]