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Ferritin 3d printed

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Coated Full Color Sandstone
Ferritin  3d printed
Ferritin  3d printed

DIGITAL PREVIEW
Not a Photo

Ferritin

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$45.00
3D printed in fully colored material with a glossy and smooth finish.
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Product Description
Ferritin is important in iron homeostasis. Its twenty-four chains of two types, H and L, assemble as a hollow shell providing an iron-storage cavity. Ferritin molecules in cells containing high levels of iron tend to be rich in L chains, and may have a long-term storage function, whereas H-rich ferritins are more active in iron metabolism. The molecular basis for the greater activity of H-rich ferritins has until now been obscure, largely because the structure of H-chain ferritin has remained unknown owing to the difficulties in obtaining crystals ordered enough for X-ray crystallographic analysis. Here we report the three-dimensional structure of a human ferritin H-chain homopolymer. By genetically engineering a change in the sequence of the intermolecular contact region, we obtained crystals isomorphous with the homologous rat L ferritin and of high enough quality for X-ray diffraction analysis. The X-ray structure of human H ferritin shows a novel metal site embedded within each of its four-helix bundles and we suggest that ferroxidase activity associated with this site accounts for its rapid uptake of iron. 
 
Details
What's in the box:
Ferritin 
Dimensions:
11.75 x 5.41 x 3.93 cm
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4.63 x 2.13 x 1.55 inches
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Rating:
Mature audiences only.
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