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LptB2FG 5X5Y 3d printed

DIGITAL PREVIEW
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Glossy Full Color Sandstone
LptB2FG  5X5Y 3d printed
LptB2FG  5X5Y 3d printed

DIGITAL PREVIEW
Not a Photo

LptB2FG 5X5Y

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$46.53
3D printed in fully colored material with a glossy and smooth finish.
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Product Description
After biosynthesis, bacterial lipopolysaccharides (LPS) are transiently anchored to the outer leaflet of the inner membrane (IM). The ATP-binding cassette (ABC) transporter LptB2FG extracts LPS molecules from the IM and transports them to the outer membrane. Here we report the crystal structure of nucleotide-free LptB2FG from Pseudomonas aeruginosa. The structure reveals that lipopolysaccharide transport proteins LptF and LptG each contain a transmembrane domain (TMD), a periplasmic ?-jellyroll-like domain and a coupling helix that interacts with LptB on the cytoplasmic side. The LptF and LptG TMDs form a large outward-facing V-shaped cavity in the IM. Mutational analyses suggest that LPS may enter the central cavity laterally, via the interface of the TMD domains of LptF and LptG, and is expelled into the ?-jellyroll-like domains upon ATP binding and hydrolysis by LptB. These studies suggest a mechanism for LPS extraction by LptB2FG that is distinct from those of classical ABC transporters that transport substrates across the IM. 
http://www.rcsb.org/pdb/explore.do?structureId=5x5y
Details
What's in the box:
Sml: LptBGF 5X5Y
Dimensions:
4.31 x 6.57 x 3.16 cm
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1.7 x 2.59 x 1.24 inches
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Success Rate:
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Rating:
Mature audiences only.
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