Hi Chris, Sorry for the late reply. Needed to do a little research... The BackBone was designed before the introduction of the Edge 1000, but it appears to just fit (see attached image). The limiting factor would be the thickness of the stem's faceplate. I was not able to find actual outside dimensions of the unit, but scaling from images usually gives me a close approximation. I've included dimensions (millimeters) in the image to compare my estimated size to the actual dimensions (assuming you have a unit to measure)...I have actually attached the Edge 1000 to a BackBone and it had plenty of clearance to the arms, although the mount was not attached to a handlebar at the time.
I would not recommend the landscape orientation. It should hold, but will not be "locked". Thanks for the questions.