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Theobromine is the active ingredient of the cacao plant, which is found in chocolate, the
tea plant, guarana berry, yerba mate, yaupon holly and the kola nut.
The earliest evidence of theobromine comsumption arose from an ancient Mayan pot
dated to 600BC. Chocolate was consumed as a bitter drink named xocolatl, and cocoa
beans were often used as currency in the pre Columbian Mesoamerican era. The Spaniards
introduced Xocolatl to Europe, the West Indies and the Philippines, which became a
popular brew by the 1700’s.
Theobromine has several potential medical uses, but is most commonly used in
combination therapy to treat high blood pressure.