This is a three-dimensional reconstruction of Feline Calicivirus bound to its cellular receptor Junctional Adhesion Molecule A, solved by cryo-electron microscopy. It is therefore an exact scale model of the virus receptor complex (approximately 2,000,000 x).
Receptor binding induces a conformational change in the capsid, this model shows the structure before the conformational change.
This structure was reported in "The cryo-electron microscopy structure of feline calicivirus bound to junctional adhesion molecule A at 9-angstrom resolution reveals receptor-induced flexibility and two distinct conformational changes in the capsid protein VP1"
Bhella D, Goodfellow IG. J Virol. 2011 Nov;85(21):11381-90
9.792 w x
9.824 d x
3.855 w x
3.868 d x