Dynein is the molecular taxi of the cell. It carries it's cargo along the Microtubules that make up the Cytoskeleton of a cell.
It is a member of a large and ancient family of proteins. Some of which form the basic of muscles.
Original Source data:
The 2.8 Å crystal structure of the dynein motor domain.
Kon, T., Oyama, T., Shimo-Kon, R., Imamula, K., Shima, T., Sutoh, K., Kurisu, G.
Journal: (2012) Nature 484: 345-350
Dyneins are microtubule-based AAA(+) motor complexes that power ciliary beating, cell division, cell migration and intracellular transport. Here we report the most complete structure obtained so far, to our knowledge, of the 380-kDa motor domain of Dictyostelium discoideum cytoplasmic dynein... [ Read More & Search PubMed Abstracts ]