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My DNA cross design has arrived [message #5537] Wed, 29 July 2009 15:19 UTC Go to next message
avatar Hogberg  is currently offline Hogberg
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Registered: July 2009
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Check it out here.

I included some electron microscope images of the original design "printed" in DNA at the 40nm scale.
Re: My DNA cross design has arrived [message #5561 is a reply to message #5537 ] Thu, 30 July 2009 11:54 UTC Go to previous messageGo to next message
avatar joris  is currently offline joris
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Wait, you're 3D printing DNA at the nanoscale? How did I miss this?
Re: My DNA cross design has arrived [message #5591 is a reply to message #5561 ] Thu, 30 July 2009 21:40 UTC Go to previous messageGo to next message
avatar Hogberg  is currently offline Hogberg
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Yes we are. We are using a self-assembly technique called DNA-origami. The technique was discovered in 2006 by this guy at caltech (Paul Rothemund) he did some nice 2D designs like a famous DNA-smiley.

In our lab (William Shihs lab at Harvard) we have been working on extending the technique to 3 dimensions. We can now build pretty complex designs, like the cross i uploaded here. The uploaded 3D model show how the main DNA chain winds its way through the design. On my webpage you can find some more info and links to our stuff if you are interested.

Some day I hope people can order nanostructures just like they order "macrostructures" from Shapeways, wouldn't that be cool?

Re: My DNA cross design has arrived [message #5598 is a reply to message #5591 ] Fri, 31 July 2009 06:58 UTC Go to previous messageGo to next message
avatar joris  is currently offline joris
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Mwah, I don't know about cool, that would be nifty I guess.

Kidding, that would be unbelievable!
Re: My DNA cross design has arrived [message #5599 is a reply to message #5537 ] Fri, 31 July 2009 08:36 UTC Go to previous messageGo to next message
avatar Ushanka  is currently offline Ushanka
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Registered: April 2009
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Wow, that was you? I saw that on Make:Blog and thought it looked amazing.
Re: My DNA cross design has arrived [message #5645 is a reply to message #5599 ] Mon, 03 August 2009 16:59 UTC Go to previous messageGo to next message
avatar gibell  is currently offline gibell
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Excellent! What is the printing cost per cm^3 for DNA? Very Happy

Since DNA is linear or 1D, I find the term "DNA Origami" to be confusing because origami is about building things with paper, a fundamentally 2D object. Why not "DNA knitting" or "DNA crochet"?
Re: My DNA cross design has arrived [message #5659 is a reply to message #5599 ] Tue, 04 August 2009 14:51 UTC Go to previous message
avatar Hogberg  is currently offline Hogberg
Messages: 3
Registered: July 2009
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Ushanka

Wow, that was you? I saw that on Make:Blog and thought it looked amazing.

Well, I'm not the original inventor or anything. Although I would say currently our lab is probably the best in the world in doing this kind of stuff . Rolling Eyes

gibell

Excellent! What is the printing cost per cm^3 for DNA?

Ahem, pretty high. The price per copy is ridiculously low though, since we routinely make about 500 billion copies in each run!

gibell

Since DNA is linear or 1D, I find the term "DNA Origami" to be confusing because origami is about building things with paper, a fundamentally 2D object. Why not "DNA knitting" or "DNA crochet"?

Its a good point. "Knitting with DNA" is actually a term we like to use.

 
   
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